Long-term balancing selection maintains trans-specific polymorphisms in the human TRIM5 gene
Long-term balancing selection maintains trans-specific polymorphisms in the human TRIM5 gene
About this item
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Author / Creator
Publisher
Berlin/Heidelberg: Springer-Verlag
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer-Verlag
Subjects
More information
Scope and Contents
Contents
The human
TRIM5
genes encodes a retroviral restriction factor (TRIM5α). Evolutionary analyses of this gene in mammals have revealed a complex and multifaceted scenario, suggesting that
TRIM5
has been the target of exceptionally strong selective pressures, possibly exerted by recurrent waves of retroviral infections.
TRIM5
displays...
Alternative Titles
Full title
Long-term balancing selection maintains trans-specific polymorphisms in the human TRIM5 gene
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_954608478
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_954608478
Other Identifiers
ISSN
0340-6717
E-ISSN
1432-1203
DOI
10.1007/s00439-010-0884-6