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Heparan sulfate 6-O-sulfotransferase 1, a gene involved in extracellular sugar modifications, is mut...

Heparan sulfate 6-O-sulfotransferase 1, a gene involved in extracellular sugar modifications, is mut...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_968164897

Heparan sulfate 6-O-sulfotransferase 1, a gene involved in extracellular sugar modifications, is mutated in patients with idiopathic hypogonadotrophic hypogonadism

About this item

Full title

Heparan sulfate 6-O-sulfotransferase 1, a gene involved in extracellular sugar modifications, is mutated in patients with idiopathic hypogonadotrophic hypogonadism

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2011-07, Vol.108 (28), p.11524-11529

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Neuronal development is the result of a multitude of neural migrations, which require extensive cell-cell communication. These processes are modulated by extracellular matrix components, such as heparan sulfate (HS) polysaccharides. HS is molecularly complex as a result of nonrandom modifications of the sugar moieties, including sulfations in speci...

Alternative Titles

Full title

Heparan sulfate 6-O-sulfotransferase 1, a gene involved in extracellular sugar modifications, is mutated in patients with idiopathic hypogonadotrophic hypogonadism

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_968164897

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_968164897

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1102284108

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