Intracisternal rSV40 administration provides effective pan-CNS transgene expression
Intracisternal rSV40 administration provides effective pan-CNS transgene expression
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
Potential genetic treatments for many generalized central nervous system (CNS) diseases require transgene expression throughout the CNS. Using oxidant stress and apoptosis caused by HIV-1 envelope gp120 as a model, we studied pan-CNS neuroprotective gene delivery into the cisterna magna (CM). Recombinant SV40 vectors carrying Cu/Zn superoxide dismu...
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Full title
Intracisternal rSV40 administration provides effective pan-CNS transgene expression
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TN_cdi_proquest_miscellaneous_968172267
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_968172267
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ISSN
0969-7128
E-ISSN
1476-5462
DOI
10.1038/gt.2011.75
