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Adenovirus-mediated Aurora A shRNA driven by stathmin promoter suppressed tumor growth and enhanced...

Adenovirus-mediated Aurora A shRNA driven by stathmin promoter suppressed tumor growth and enhanced...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_968176065

Adenovirus-mediated Aurora A shRNA driven by stathmin promoter suppressed tumor growth and enhanced paclitaxel chemotherapy sensitivity in human breast carcinoma cells

About this item

Full title

Adenovirus-mediated Aurora A shRNA driven by stathmin promoter suppressed tumor growth and enhanced paclitaxel chemotherapy sensitivity in human breast carcinoma cells

Publisher

New York: Nature Publishing Group US

Journal title

Cancer gene therapy, 2012-04, Vol.19 (4), p.271-281

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Aurora A has multiple key functions in tumor initiation and progression and is overexpressed in many cancers. Several ongoing clinical trials are assessing the unique therapeutic potential of Aurora-based targeted therapy, but several severe adverse events such as hematopoietic toxicity have been observed in the early-phase clinical trials because...

Alternative Titles

Full title

Adenovirus-mediated Aurora A shRNA driven by stathmin promoter suppressed tumor growth and enhanced paclitaxel chemotherapy sensitivity in human breast carcinoma cells

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_968176065

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_968176065

Other Identifiers

ISSN

0929-1903

E-ISSN

1476-5500

DOI

10.1038/cgt.2011.89

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