Clinical Trials and Studies; Role of calcium in familial Alzheimer's disease clarified, pointing to...
Clinical Trials and Studies; Role of calcium in familial Alzheimer's disease clarified, pointing to new therapeutics
About this item
Full title
Publisher
Atlanta: NewsRx
Journal title
Language
English
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Publication information
Publisher
Atlanta: NewsRx
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Scope and Contents
Contents
The two proteins, called PS1 and PS2 (presenilin 1 and 2), interact with a calcium release channel, the inositol trisphosphate receptor (IP3R), in the endoplasmic reticulum. Mutant PS1 and PS2 increase the activity of the IP3R, in turn increasing calcium levels in the cell. "We set out to answer the question: Is increased calcium signaling, as a re...
Alternative Titles
Full title
Clinical Trials and Studies; Role of calcium in familial Alzheimer's disease clarified, pointing to new therapeutics
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TN_cdi_proquest_wirefeeds_1526220170
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_wirefeeds_1526220170
Other Identifiers
ISSN
1543-6608
E-ISSN
1543-6616
