Genetics Genomics; Human hepatocytes proposed for assessing genetic polymorphism of CYP2D6 substrate...
Genetics Genomics; Human hepatocytes proposed for assessing genetic polymorphism of CYP2D6 substrates
About this item
Full title
Genetics Genomics; Human hepatocytes proposed for assessing genetic polymorphism of CYP2D6 substrates
Publisher
Atlanta: NewsRx
Journal title
World Disease Weekly, 2005, p.806
Language
English
Formats
Publication information
Publisher
Atlanta: NewsRx
More information
Scope and Contents
Contents
"The contributions in hepatocytes were," they determined, "19.2% for propranolol at 0.05 mcM and 36.7-76.3% for propafenone at 0.05- 1.0 mcM, and smaller than the contribution in microsomes, unlike the case for metoprolol. The differences between microsomes and hepatocytes were attributable to conjugate formation. The CYP2D6 contributions in hepato...
Alternative Titles
Full title
Genetics Genomics; Human hepatocytes proposed for assessing genetic polymorphism of CYP2D6 substrates
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_wirefeeds_210007229
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_wirefeeds_210007229
Other Identifiers
ISSN
1553-6963
E-ISSN
1553-6971
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