Poly(ADP-ribose) Polymerases; Toronto researchers obtain detailed molecular 'signature' for Tankyras...
Poly(ADP-ribose) Polymerases; Toronto researchers obtain detailed molecular 'signature' for Tankyrase
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Publisher
Atlanta: NewsRx
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Language
English
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Publisher
Atlanta: NewsRx
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Contents
Initially intrigued by Tankyrase because of its involvement in cherubism (a rare genetic disorder caused by mutations in the signaling protein 3BP2), the researchers built upon the findings of Dr. [Robert Rottapel]'s laboratory. This laboratory found that Tankyrase normally recognizes 3BP2 and targets it for destruction. The amino acids mutated in...
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Full title
Poly(ADP-ribose) Polymerases; Toronto researchers obtain detailed molecular 'signature' for Tankyrase
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TN_cdi_proquest_wirefeeds_912177549
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_wirefeeds_912177549
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ISSN
1531-6386
E-ISSN
1532-4664