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Poly(ADP-ribose) Polymerases; Toronto researchers obtain detailed molecular 'signature' for Tankyras...

Poly(ADP-ribose) Polymerases; Toronto researchers obtain detailed molecular 'signature' for Tankyras...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_wirefeeds_912177549

Poly(ADP-ribose) Polymerases; Toronto researchers obtain detailed molecular 'signature' for Tankyrase

About this item

Full title

Poly(ADP-ribose) Polymerases; Toronto researchers obtain detailed molecular 'signature' for Tankyrase

Publisher

Atlanta: NewsRx

Journal title

Obesity, Fitness & Wellness Week, 2011, p.2197

Language

English

Publication information

Publisher

Atlanta: NewsRx

More information

Scope and Contents

Contents

Initially intrigued by Tankyrase because of its involvement in cherubism (a rare genetic disorder caused by mutations in the signaling protein 3BP2), the researchers built upon the findings of Dr. [Robert Rottapel]'s laboratory. This laboratory found that Tankyrase normally recognizes 3BP2 and targets it for destruction. The amino acids mutated in...

Alternative Titles

Full title

Poly(ADP-ribose) Polymerases; Toronto researchers obtain detailed molecular 'signature' for Tankyrase

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_wirefeeds_912177549

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_wirefeeds_912177549

Other Identifiers

ISSN

1531-6386

E-ISSN

1532-4664

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