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Investigation of bioavailability and pharmacokinetics of treosulfan capsules in patients with relaps...

Investigation of bioavailability and pharmacokinetics of treosulfan capsules in patients with relaps...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_10854136

Investigation of bioavailability and pharmacokinetics of treosulfan capsules in patients with relapsed ovarian cancer

About this item

Full title

Investigation of bioavailability and pharmacokinetics of treosulfan capsules in patients with relapsed ovarian cancer

Publisher

Berlin: Springer

Journal title

Cancer chemotherapy and pharmacology, 2000, Vol.45 (6), p.483-488

Language

English

Formats

Publication information

Publisher

Berlin: Springer

More information

Scope and Contents

Contents

Treosulfan (L-threitol-1,4-bis-methanesulfonate, Ovastat) is a prodrug of a bifunctional alkylating agent with activity in ovarian carcinoma and other solid tumors. In a pharmacologic study of the bioavailability of treosulfan in a capsule formulation, patients with relapsed ovarian carcinoma were treated with alternating doses of oral and intraven...

Alternative Titles

Full title

Investigation of bioavailability and pharmacokinetics of treosulfan capsules in patients with relapsed ovarian cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_10854136

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_10854136

Other Identifiers

ISSN

0344-5704

E-ISSN

1432-0843

DOI

10.1007/s002800051023

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