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Retinoid-Related Orphan Receptor γ (RORγ ) Is Essential for Lymphoid Organogenesis and Controls Apop...

Retinoid-Related Orphan Receptor γ (RORγ ) Is Essential for Lymphoid Organogenesis and Controls Apop...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_10963675

Retinoid-Related Orphan Receptor γ (RORγ ) Is Essential for Lymphoid Organogenesis and Controls Apoptosis during Thymopoiesis

About this item

Full title

Retinoid-Related Orphan Receptor γ (RORγ ) Is Essential for Lymphoid Organogenesis and Controls Apoptosis during Thymopoiesis

Publisher

United States: National Academy of Sciences of the United States of America

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2000-08, Vol.97 (18), p.10132-10137

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences of the United States of America

More information

Scope and Contents

Contents

To identify the physiological functions of the retinoid-related orphan receptor γ (RORγ ), a member of the nuclear receptor superfamily, mice deficient in RORγ function were generated by targeted disruption. RORγ-/-mice lack peripheral and mesenteric lymph nodes and Peyer's patches, indicating that RORγ expression is indispensable for lymph node or...

Alternative Titles

Full title

Retinoid-Related Orphan Receptor γ (RORγ ) Is Essential for Lymphoid Organogenesis and Controls Apoptosis during Thymopoiesis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_10963675

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_10963675

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.97.18.10132

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