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Functional Interaction between c-Abl and the p21-Activated Protein Kinase γ-PAK

Functional Interaction between c-Abl and the p21-Activated Protein Kinase γ-PAK

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_11121037

Functional Interaction between c-Abl and the p21-Activated Protein Kinase γ-PAK

About this item

Full title

Functional Interaction between c-Abl and the p21-Activated Protein Kinase γ-PAK

Publisher

United States: National Academy of Sciences of the United States of America

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2000-12, Vol.97 (26), p.14346-14351

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences of the United States of America

More information

Scope and Contents

Contents

A member of the p21-activated protein kinase (PAK) family, γ-PAK has cytostatic properties and is activated by cellular stresses such as hyperosmolarity or DNA damage. We report herein that γ-PAK is associated in vivo with the nonreceptor protein tyrosine kinase c-AbI. γ-PAK phosphorylates c-AbI on sites located in the kinase domain, in a region th...

Alternative Titles

Full title

Functional Interaction between c-Abl and the p21-Activated Protein Kinase γ-PAK

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_11121037

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_11121037

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.97.26.14346

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