An Essential Amino Acid Residue in the Protein Translocation Channel Revealed by Targeted Random Mut...
An Essential Amino Acid Residue in the Protein Translocation Channel Revealed by Targeted Random Mutagenesis of SecY
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
The SecY/Sec61α family of membrane proteins are the central subunits of the putative protein translocation channel. We introduced random mutations into a segment of Escherichia coli SecY within its cytoplasmic domain 5, which was shown previously to be important for the SecA-dependent translocation activity. Mutations were classified into those ret...
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Full title
An Essential Amino Acid Residue in the Protein Translocation Channel Revealed by Targeted Random Mutagenesis of SecY
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TN_cdi_pubmed_primary_11309495
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_11309495
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.081617398
