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Pim Serine/Threonine Kinases Regulate the Stability of Socs-1 Protein

Pim Serine/Threonine Kinases Regulate the Stability of Socs-1 Protein

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_11854514

Pim Serine/Threonine Kinases Regulate the Stability of Socs-1 Protein

About this item

Full title

Pim Serine/Threonine Kinases Regulate the Stability of Socs-1 Protein

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2002-02, Vol.99 (4), p.2175-2180

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Studies of SOCS-1-deficient mice have implicated Socs-1 in the suppression of JAK-STAT (Janus tyrosine kinase-signal transducers and activators of transcription) signaling and T cell development. It has been suggested that the levels of Socs-1 protein may be regulated through the proteasome pathway. Here we show that Socs-1 interacts with members o...

Alternative Titles

Full title

Pim Serine/Threonine Kinases Regulate the Stability of Socs-1 Protein

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_11854514

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_11854514

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.042035699

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