Enhanced Insulin Sensitivity in Mice Lacking Ganglioside GM3
Enhanced Insulin Sensitivity in Mice Lacking Ganglioside GM3
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Gangliosides are sialic acid-containing glycosphingolipids that are present on all mammalian plasma membranes where they participate in recognition and signaling activities. We have established mutant mice that lack GM3 synthase (CMP-NeuAc:lactosylceramide α2,3-sialyltransferase; EC 2.4.99.-). These mutant mice were unable to synthesize GM3 ganglio...
Alternative Titles
Full title
Enhanced Insulin Sensitivity in Mice Lacking Ganglioside GM3
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TN_cdi_pubmed_primary_12629211
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_12629211
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0635898100
