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β-Lapachone Reduces Endotoxin-induced Macrophage Activation and Lung Edema and Mortality

β-Lapachone Reduces Endotoxin-induced Macrophage Activation and Lung Edema and Mortality

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_12724123

β-Lapachone Reduces Endotoxin-induced Macrophage Activation and Lung Edema and Mortality

About this item

Full title

β-Lapachone Reduces Endotoxin-induced Macrophage Activation and Lung Edema and Mortality

Publisher

New York, NY: American Lung Association

Journal title

American journal of respiratory and critical care medicine, 2003-07, Vol.168 (1), p.85-91

Language

English

Formats

Publication information

Publisher

New York, NY: American Lung Association

More information

Scope and Contents

Contents

beta-Lapachone, a 1,2-naphthoquinone, is a novel chemotherapeutic agent. It has been shown to be capable of suppressing inducible nitric oxide synthase expression and function in rat alveolar macrophages. The authors further performed experiments to examine the molecular mechanism of beta-lapachone on LPS-induced responses in rat alveolar macrophag...

Alternative Titles

Full title

β-Lapachone Reduces Endotoxin-induced Macrophage Activation and Lung Edema and Mortality

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_12724123

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_12724123

Other Identifiers

ISSN

1073-449X

E-ISSN

1535-4970

DOI

10.1164/rccm.200209-1051OC

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