Regulated expression of erythropoietin from an AAV vector safely improves the anemia of β-thalassemi...
Regulated expression of erythropoietin from an AAV vector safely improves the anemia of β-thalassemia in a mouse model
About this item
Full title
Author / Creator
Publisher
United States: Elsevier Inc
Journal title
Language
English
Formats
Publication information
Publisher
United States: Elsevier Inc
Subjects
More information
Scope and Contents
Contents
In vivo gene transfer is being considered in the systemic delivery of therapeutic proteins. This report evaluates the use of AAV vectors administered into muscle to deliver erythropoietin (Epo) for the treatment of anemia in a mouse model of β-thalassemia. Injection of vector expressing Epo from a constitutive promoter resulted in Epo overproductio...
Alternative Titles
Full title
Regulated expression of erythropoietin from an AAV vector safely improves the anemia of β-thalassemia in a mouse model
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmed_primary_12727112
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_12727112
Other Identifiers
ISSN
1525-0016
E-ISSN
1525-0024
DOI
10.1016/S1525-0016(03)00043-1
