Transcriptome Signature of Irreversible Senescence in Human Papillomavirus-Positive Cervical Cancer...
Transcriptome Signature of Irreversible Senescence in Human Papillomavirus-Positive Cervical Cancer Cells
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
A frequent characteristic of human papillomavirus (HPV)-positive cervical cancers is the loss of viral E2 gene expression in HPV-infected cervical epithelial cells as a consequence of viral DNA integration into the cellular genome. The expression of E2 in HPV-positive cancer cells results in the repression of the viral E6/E7 oncogenes, activation o...
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Full title
Transcriptome Signature of Irreversible Senescence in Human Papillomavirus-Positive Cervical Cancer Cells
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TN_cdi_pubmed_primary_12756294
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_12756294
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1232309100
