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Protein Tyrosine Phosphatase RQ Is a Phosphatidylinositol Phosphatase That Can Regulate Cell Surviva...

Protein Tyrosine Phosphatase RQ Is a Phosphatidylinositol Phosphatase That Can Regulate Cell Surviva...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_12802008

Protein Tyrosine Phosphatase RQ Is a Phosphatidylinositol Phosphatase That Can Regulate Cell Survival and Proliferation

About this item

Full title

Protein Tyrosine Phosphatase RQ Is a Phosphatidylinositol Phosphatase That Can Regulate Cell Survival and Proliferation

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2003-06, Vol.100 (13), p.7563-7568

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Protein tyrosine phosphatase RQ (PTPRQ) was initially identified as a protein tyrosine phosphatase (PTPase)-like protein that is up-regulated in a model of renal injury. Here we present evidence that, like PTEN, the biologically important enzymatic activity of PTPRQ is as a phosphatidylinositol phosphatase (PIPase). The PIPase specificity of PTPRQ...

Alternative Titles

Full title

Protein Tyrosine Phosphatase RQ Is a Phosphatidylinositol Phosphatase That Can Regulate Cell Survival and Proliferation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_12802008

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_12802008

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1336511100

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