Molecular Mechanism for Activation of Superoxide-producing NADPH Oxidases
Molecular Mechanism for Activation of Superoxide-producing NADPH Oxidases
About this item
Full title
Molecular Mechanism for Activation of Superoxide-producing NADPH Oxidases
Author / Creator
Publisher
United States
Journal title
Molecules and cells, 2003-12, Vol.16 (3), p.271-277
Language
English
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Publisher
United States
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Scope and Contents
Contents
The membrane-integrated protein gp91phox, existing as a heterodimer with p22phox, functions as the catalytic core of the phagocyte NADPH oxidase, which plays a crucial role in host defence. The oxidase, dormant in resting cells, becomes activated to produce superoxide, a precursor of microbicidal oxidants, by interacting with the adaptor proteins p...
Alternative Titles
Full title
Molecular Mechanism for Activation of Superoxide-producing NADPH Oxidases
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_pubmed_primary_14744014
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_14744014
Other Identifiers
ISSN
1016-8478
DOI
10.1016/s1016-8478(23)13800-3
