Nitrosative Stress Linked to Sporadic Parkinson's Disease: S-Nitrosylation of Parkin Regulates Its E...
Nitrosative Stress Linked to Sporadic Parkinson's Disease: S-Nitrosylation of Parkin Regulates Its E3 Ubiquitin Ligase Activity
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Many hereditary and sporadic neurodegenerative disorders are characterized by the accumulation of aberrant proteins. In sporadic Parkinson's disease, representing the most prevalent movement disorder, oxidative and nitrosative stress are believed to contribute to disease pathogenesis, but the exact molecular basis for protein aggregation remains un...
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Nitrosative Stress Linked to Sporadic Parkinson's Disease: S-Nitrosylation of Parkin Regulates Its E3 Ubiquitin Ligase Activity
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TN_cdi_pubmed_primary_15252205
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_15252205
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0404161101