Global and Hox-Specific Roles for the MLL1 Methyltransferase
Global and Hox-Specific Roles for the MLL1 Methyltransferase
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
The mixed-lineage leukemia (MLL1/ALL-1/HRX) histone methyltransferase is involved in the epigenetic maintenance of transcriptional memory and the pathogenesis of human leukemias. To understand its role in cell type specification, we determined the human genomic binding sites of MLL1. We found that MLL1 functions as a human equivalent of yeast Set1....
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Full title
Global and Hox-Specific Roles for the MLL1 Methyltransferase
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TN_cdi_pubmed_primary_15941828
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_15941828
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0503072102
