Antioxidants Modulate Mitochondrial PKA and Increase CREB Binding to D-Loop DNA of the Mitochondrial...
Antioxidants Modulate Mitochondrial PKA and Increase CREB Binding to D-Loop DNA of the Mitochondrial Genome in Neurons
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
The protein kinase A (PKA) and the cAMP response element (CRE) binding protein (CREB) signaling pathways mediate plasticity and prosurvival responses in neurons through their ability to regulate gene expression. The PKA-CREB signaling mechanism has been well characterized in terms of nuclear gene expression. We show that the PKA catalytic and regul...
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Full title
Antioxidants Modulate Mitochondrial PKA and Increase CREB Binding to D-Loop DNA of the Mitochondrial Genome in Neurons
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TN_cdi_pubmed_primary_16169904
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_16169904
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0502878102
