HSP72 protects against obesity-induced insulin resistance
HSP72 protects against obesity-induced insulin resistance
About this item
Full title
Author / Creator
Chung, Jason , Nguyen, Anh-Khoi , Henstridge, Darren C , Holmes, Anna G , Chan, M.H. Stanley , Mesa, Jose L , Lancaster, Graeme I , Southgate, Robert J , Bruce, Clinton R , Duffy, Stephen J , Horvath, Ibolya , Mestril, Ruben , Watt, Matthew J , Hooper, Philip L , Kingwell, Bronwyn A , Vigh, Laszlo , Hevener, Andrea and Febbraio, Mark A
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Patients with type 2 diabetes have reduced gene expression of heat shock protein (HSP) 72, which correlates with reduced insulin sensitivity. Heat therapy, which activates HSP72, improves clinical parameters in these patients. Activation of several inflammatory signaling proteins such as c-jun amino terminal kinase (JNK), inhibitor of κB kinase, an...
Alternative Titles
Full title
HSP72 protects against obesity-induced insulin resistance
Authors, Artists and Contributors
Author / Creator
Nguyen, Anh-Khoi
Henstridge, Darren C
Holmes, Anna G
Chan, M.H. Stanley
Mesa, Jose L
Lancaster, Graeme I
Southgate, Robert J
Bruce, Clinton R
Duffy, Stephen J
Horvath, Ibolya
Mestril, Ruben
Watt, Matthew J
Hooper, Philip L
Kingwell, Bronwyn A
Vigh, Laszlo
Hevener, Andrea
Febbraio, Mark A
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmed_primary_18223156
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_18223156
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0705799105
