Membrane curvature induced by Arf1-GTP is essential for vesicle formation
Membrane curvature induced by Arf1-GTP is essential for vesicle formation
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
The GTPase Arf1 is considered as a molecular switch that regulates binding and release of coat proteins that polymerize on membranes to form transport vesicles. Here, we show that Arf1-GTP induces positive membrane curvature and find that the small GTPase can dimerize dependent on GTP. Investigating a possible link between Arf dimerization and curv...
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Full title
Membrane curvature induced by Arf1-GTP is essential for vesicle formation
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TN_cdi_pubmed_primary_18689681
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_18689681
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0805182105
