TGFbeta-stimulated Smad1/5 phosphorylation requires the ALK5 L45 loop and mediates the pro-migratory...
TGFbeta-stimulated Smad1/5 phosphorylation requires the ALK5 L45 loop and mediates the pro-migratory TGFbeta switch
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Publisher
England
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Language
English
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Publisher
England
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Contents
During the course of breast cancer progression, normally dormant tumour-promoting effects of transforming growth factor beta (TGFbeta), including migration, invasion, and metastasis are unmasked. In an effort to identify mechanisms that regulate the pro-migratory TGFbeta 'switch' in mammary epithelial cells in vitro, we found that TGFbeta stimulate...
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Full title
TGFbeta-stimulated Smad1/5 phosphorylation requires the ALK5 L45 loop and mediates the pro-migratory TGFbeta switch
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TN_cdi_pubmed_primary_19096363
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_19096363
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E-ISSN
1460-2075
DOI
10.1038/emboj.2008.266