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TGFbeta-stimulated Smad1/5 phosphorylation requires the ALK5 L45 loop and mediates the pro-migratory...

TGFbeta-stimulated Smad1/5 phosphorylation requires the ALK5 L45 loop and mediates the pro-migratory...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_19096363

TGFbeta-stimulated Smad1/5 phosphorylation requires the ALK5 L45 loop and mediates the pro-migratory TGFbeta switch

About this item

Full title

TGFbeta-stimulated Smad1/5 phosphorylation requires the ALK5 L45 loop and mediates the pro-migratory TGFbeta switch

Publisher

England

Journal title

The EMBO journal, 2009-01, Vol.28 (2), p.88

Language

English

Formats

Publication information

Publisher

England

More information

Scope and Contents

Contents

During the course of breast cancer progression, normally dormant tumour-promoting effects of transforming growth factor beta (TGFbeta), including migration, invasion, and metastasis are unmasked. In an effort to identify mechanisms that regulate the pro-migratory TGFbeta 'switch' in mammary epithelial cells in vitro, we found that TGFbeta stimulate...

Alternative Titles

Full title

TGFbeta-stimulated Smad1/5 phosphorylation requires the ALK5 L45 loop and mediates the pro-migratory TGFbeta switch

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_19096363

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_19096363

Other Identifiers

E-ISSN

1460-2075

DOI

10.1038/emboj.2008.266

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