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A-94964, a Novel Inhibitor of Bacterial Translocase I, Produced by Streptomyces sp. SANK 60404: I. T...

A-94964, a Novel Inhibitor of Bacterial Translocase I, Produced by Streptomyces sp. SANK 60404: I. T...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_19160520

A-94964, a Novel Inhibitor of Bacterial Translocase I, Produced by Streptomyces sp. SANK 60404: I. Taxonomy, Isolation and Biological Activity

About this item

Full title

A-94964, a Novel Inhibitor of Bacterial Translocase I, Produced by Streptomyces sp. SANK 60404: I. Taxonomy, Isolation and Biological Activity

Publisher

London: Nature Publishing Group UK

Journal title

Journal of antibiotics, 2008-09, Vol.61 (9), p.537-544

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Bacterial phospho-
N
-acetylmuramyl-pentapeptide translocase (translocase I: EC 2.7.8.13) is a key enzyme in peptidoglycan biosynthesis, and a known target of antibiotics. Here we report a novel nucleoside inhibitor against translocase I, A-94964, isolated from the culture broth of the strain
Streptomyces
sp. SANK 60404. A-94964 inhibit...

Alternative Titles

Full title

A-94964, a Novel Inhibitor of Bacterial Translocase I, Produced by Streptomyces sp. SANK 60404: I. Taxonomy, Isolation and Biological Activity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_19160520

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_19160520

Other Identifiers

ISSN

0021-8820

E-ISSN

1881-1469

DOI

10.1038/ja.2008.71

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