role for Orai in TRPC-mediated Ca²⁺ entry suggests that a TRPC:Orai complex may mediate store and re...
role for Orai in TRPC-mediated Ca²⁺ entry suggests that a TRPC:Orai complex may mediate store and receptor operated Ca²⁺ entry
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
TRPC and Orai proteins have both been proposed to form Ca²⁺-selective, store-operated calcium entry (SOCE) channels that are activated by store-depletion with Ca²⁺ chelators or calcium pump inhibitors. In contrast, only TRPC proteins have been proposed to form nonselective receptor-operated calcium entry (ROCE) cation channels that are activated by...
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Full title
role for Orai in TRPC-mediated Ca²⁺ entry suggests that a TRPC:Orai complex may mediate store and receptor operated Ca²⁺ entry
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TN_cdi_pubmed_primary_19221033
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_19221033
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0813346106