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role for Orai in TRPC-mediated Ca²⁺ entry suggests that a TRPC:Orai complex may mediate store and re...

role for Orai in TRPC-mediated Ca²⁺ entry suggests that a TRPC:Orai complex may mediate store and re...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_19221033

role for Orai in TRPC-mediated Ca²⁺ entry suggests that a TRPC:Orai complex may mediate store and receptor operated Ca²⁺ entry

About this item

Full title

role for Orai in TRPC-mediated Ca²⁺ entry suggests that a TRPC:Orai complex may mediate store and receptor operated Ca²⁺ entry

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2009-03, Vol.106 (9), p.3202-3206

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

TRPC and Orai proteins have both been proposed to form Ca²⁺-selective, store-operated calcium entry (SOCE) channels that are activated by store-depletion with Ca²⁺ chelators or calcium pump inhibitors. In contrast, only TRPC proteins have been proposed to form nonselective receptor-operated calcium entry (ROCE) cation channels that are activated by...

Alternative Titles

Full title

role for Orai in TRPC-mediated Ca²⁺ entry suggests that a TRPC:Orai complex may mediate store and receptor operated Ca²⁺ entry

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_19221033

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_19221033

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0813346106

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