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Genome-Wide Discovery of Functional Transcription Factor Binding Sites by Comparative Genomics: The...

Genome-Wide Discovery of Functional Transcription Factor Binding Sites by Comparative Genomics: The...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_19282476

Genome-Wide Discovery of Functional Transcription Factor Binding Sites by Comparative Genomics: The Case of Stat3

About this item

Full title

Genome-Wide Discovery of Functional Transcription Factor Binding Sites by Comparative Genomics: The Case of Stat3

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2009-03, Vol.106 (13), p.5117-5122

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

The identification of direct targets of transcription factors is a key problem in the study of gene regulatory networks. However, the use of high throughput experimental methods, such as ChlP-chip and ChlP-sequencing, is limited by their high cost and strong dependence on cellular type and context. We developed a computational method for the genome...

Alternative Titles

Full title

Genome-Wide Discovery of Functional Transcription Factor Binding Sites by Comparative Genomics: The Case of Stat3

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_19282476

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_19282476

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0900473106

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