Activation of the SARS coronavirus spike protein via sequential proteolytic cleavage at two distinct...
Activation of the SARS coronavirus spike protein via sequential proteolytic cleavage at two distinct sites
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
The coronavirus spike protein (S) plays a key role in the early steps of viral infection, with the S1 domain responsible for receptor binding and the S2 domain mediating membrane fusion. In some cases, the S protein is proteolytically cleaved at the S1-S2 boundary. In the case of the severe acute respiratory syndrome coronavirus (SARS-CoV), it has...
Alternative Titles
Full title
Activation of the SARS coronavirus spike protein via sequential proteolytic cleavage at two distinct sites
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Author / Creator
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Record Identifier
TN_cdi_pubmed_primary_19321428
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_19321428
Other Identifiers
ISSN
0027-8424,1091-6490
E-ISSN
1091-6490
DOI
10.1073/pnas.0809524106
