Genetic and antibody-mediated reprogramming of natural killer cell missing-self recognition in vivo
Genetic and antibody-mediated reprogramming of natural killer cell missing-self recognition in vivo
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Full title
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Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publication information
Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Natural killer (NK) cells are lymphocytes of the innate immune system able to recognize and kill tumors lacking self-MHC class I molecules. This "missing-self" recognition is mediated by the lack of engagement of MHC class I-specific inhibitory NK cell receptors that include the killer cell Ig-like receptors (KIR) in humans and Ly49 molecules in mi...
Alternative Titles
Full title
Genetic and antibody-mediated reprogramming of natural killer cell missing-self recognition in vivo
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Primary Identifiers
Record Identifier
TN_cdi_pubmed_primary_19561305
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_19561305
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0901653106
