TRPV1-expressing primary afferents generate behavioral responses to pruritogens via multiple mechani...
TRPV1-expressing primary afferents generate behavioral responses to pruritogens via multiple mechanisms
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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The mechanisms that generate itch are poorly understood at both the molecular and cellular levels despite its clinical importance. To explore the peripheral neuronal mechanisms underlying itch, we assessed the behavioral responses (scratching) produced by s.c. injection of various pruritogens in PLCβ3- or TRPV1-deficient mice. We provide evidence t...
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Full title
TRPV1-expressing primary afferents generate behavioral responses to pruritogens via multiple mechanisms
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TN_cdi_pubmed_primary_19564617
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_19564617
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0905605106
