single modular serine protease integrates signals from pattern-recognition receptors upstream of the...
single modular serine protease integrates signals from pattern-recognition receptors upstream of the Drosophila Toll pathway
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
The Drosophila Toll receptor does not interact directly with microbial determinants, but is instead activated by a cleaved form of the cytokine-like molecule Spätzle. During the immune response, Spätzle is processed by complex cascades of serine proteases, which are activated by secreted pattern-recognition receptors. Here, we demonstrate the ess...
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Full title
single modular serine protease integrates signals from pattern-recognition receptors upstream of the Drosophila Toll pathway
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Record Identifier
TN_cdi_pubmed_primary_19590012
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_19590012
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0901924106
