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hyperfused mitochondrial state achieved at G₁-S regulates cyclin E buildup and entry into S phase

hyperfused mitochondrial state achieved at G₁-S regulates cyclin E buildup and entry into S phase

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_19617534

hyperfused mitochondrial state achieved at G₁-S regulates cyclin E buildup and entry into S phase

About this item

Full title

hyperfused mitochondrial state achieved at G₁-S regulates cyclin E buildup and entry into S phase

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2009-07, Vol.106 (29), p.11960-11965

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Mitochondria undergo fission-fusion events that render these organelles highly dynamic in cells. We report a relationship between mitochondrial form and cell cycle control at the G₁-S boundary. Mitochondria convert from isolated, fragmented elements into a hyperfused, giant network at G₁-S transition. The network is electrically continuous and has...

Alternative Titles

Full title

hyperfused mitochondrial state achieved at G₁-S regulates cyclin E buildup and entry into S phase

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_19617534

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_19617534

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0904875106

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