Markedly Enhanced Colon Tumorigenesis in$Apc^{Min} $Mice Lacking Glutathione S-Transferase Pi
Markedly Enhanced Colon Tumorigenesis in$Apc^{Min} $Mice Lacking Glutathione S-Transferase Pi
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Glutathione transferases are a multigene family of proteins that catalyze the conjugation of toxic electrophiles and carcinogens to glutathione. Glutathione transferase Pi (GSTP) is commonly overexpressed in human tumors and there is emerging evidence that the enzyme has additional cellular functions in addition to its role in drug and carcinogen d...
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Full title
Markedly Enhanced Colon Tumorigenesis in$Apc^{Min} $Mice Lacking Glutathione S-Transferase Pi
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TN_cdi_pubmed_primary_19915149
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_19915149
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0911351106
