Alterations of the Notch pathway in lung cancer
Alterations of the Notch pathway in lung cancer
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Notch signaling regulates cell specification and homeostasis of stem cell compartments, and it is counteracted by the cell fate determinant Numb. Both Numb and Notch have been implicated in human tumors. Here, we show that Notch signaling is altered in approximately one third of non-small-cell lung carcinomas (NSCLCs), which are the leading cause o...
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Full title
Alterations of the Notch pathway in lung cancer
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Record Identifier
TN_cdi_pubmed_primary_20007775
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_20007775
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0907781106