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Two isoforms of human RNA polymerase III with specific functions in cell growth and transformation

Two isoforms of human RNA polymerase III with specific functions in cell growth and transformation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_20154270

Two isoforms of human RNA polymerase III with specific functions in cell growth and transformation

About this item

Full title

Two isoforms of human RNA polymerase III with specific functions in cell growth and transformation

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2010-03, Vol.107 (9), p.4176-4181

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Transcription in eukaryotic nuclei is carried out by DNA-dependent RNA polymerases I, II, and III. Human RNA polymerase III (Pol III) transcribes small untranslated RNAs that include tRNAs, 5S RNA, U6 RNA, and some microRNAs. Increased Pol III transcription has been reported to accompany or cause cell transformation. Here we describe a Pol III subu...

Alternative Titles

Full title

Two isoforms of human RNA polymerase III with specific functions in cell growth and transformation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_20154270

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_20154270

Other Identifiers

ISSN

0027-8424,1091-6490

E-ISSN

1091-6490

DOI

10.1073/pnas.0914980107

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