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Dissecting the involvement of tropomyosin-related kinase A and p75 neurotrophin receptor signaling i...

Dissecting the involvement of tropomyosin-related kinase A and p75 neurotrophin receptor signaling i...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_20566851

Dissecting the involvement of tropomyosin-related kinase A and p75 neurotrophin receptor signaling in NGF deficit-induced neurodegeneration

About this item

Full title

Dissecting the involvement of tropomyosin-related kinase A and p75 neurotrophin receptor signaling in NGF deficit-induced neurodegeneration

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2010-07, Vol.107 (27), p.12299-12304

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

NGF, the principal neurotrophic factor for basal forebrain cholinergic neurons (BFCNs), has been correlated to Alzheimer's disease (AD) because of the selective vulnerability of BFCNs in AD. These correlative links do not substantiate a comprehensive cause—effect mechanism connecting NGF deficit to overall AD neurodegeneration. A demonstration that...

Alternative Titles

Full title

Dissecting the involvement of tropomyosin-related kinase A and p75 neurotrophin receptor signaling in NGF deficit-induced neurodegeneration

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_20566851

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_20566851

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1007181107

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