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Pheochromocytoma in rats with multiple endocrine neoplasia (MENX) shares gene expression patterns wi...

Pheochromocytoma in rats with multiple endocrine neoplasia (MENX) shares gene expression patterns wi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_20937862

Pheochromocytoma in rats with multiple endocrine neoplasia (MENX) shares gene expression patterns with human pheochromocytoma

About this item

Full title

Pheochromocytoma in rats with multiple endocrine neoplasia (MENX) shares gene expression patterns with human pheochromocytoma

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2010-10, Vol.107 (43), p.18493-18498

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Pheochromocytomas are rare neoplasias of neural crest origin arising from chromaffin cells of the adrenal medulla and sympathetic ganglia (extra-adrenal pheochromocytoma). Pheochromocytoma that develop in rats homozygous for a loss-of-function mutation in p27Kip1 (MENX syndrome) show a clear progression from hyperplasia to tumor, offering the possi...

Alternative Titles

Full title

Pheochromocytoma in rats with multiple endocrine neoplasia (MENX) shares gene expression patterns with human pheochromocytoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_20937862

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_20937862

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1003956107

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