Pheochromocytoma in rats with multiple endocrine neoplasia (MENX) shares gene expression patterns wi...
Pheochromocytoma in rats with multiple endocrine neoplasia (MENX) shares gene expression patterns with human pheochromocytoma
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Author / Creator
Molatore, Sara , Liyanarachchi, Sandya , Irmler, Martin , Perren, Aurel , Mannelli, Massimo , Ercolino, Tonino , Beuschlein, Felix , Jarzab, Barbara , Wloch, Jan , Ziaja, Jacek , Zoubaa, Saida , Neff, Frauke , Beckers, Johannes , Höfler, Heinz , Atkinson, Michael J. , Pellegata, Natalia S. and de la Chapelle, Albert
Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Pheochromocytomas are rare neoplasias of neural crest origin arising from chromaffin cells of the adrenal medulla and sympathetic ganglia (extra-adrenal pheochromocytoma). Pheochromocytoma that develop in rats homozygous for a loss-of-function mutation in p27Kip1 (MENX syndrome) show a clear progression from hyperplasia to tumor, offering the possi...
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Full title
Pheochromocytoma in rats with multiple endocrine neoplasia (MENX) shares gene expression patterns with human pheochromocytoma
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TN_cdi_pubmed_primary_20937862
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_20937862
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1003956107