Myelination transition zone astrocytes are constitutively phagocytic and have synuclein dependent re...
Myelination transition zone astrocytes are constitutively phagocytic and have synuclein dependent reactivity in glaucoma
About this item
Full title
Author / Creator
Nguyen, Judy V. , Soto, Ileana , Kim, Keun-Young , Bushong, Eric A. , Oglesby, Ericka , Valiente-Soriano, Francisco J. , Yang, Zhiyong , Davis, Chung-ha O. , Bedont, Joseph L. , Son, Janice L. , Wei, John O. , Buchman, Vladimir L. , Zack, Donald J. , Vidal-Sanz, Manuel , Ellisman, Mark H. , Marsh-Armstrong, Nicholas and Cepko, Constance L.
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Optic nerve head (ONH) astrocytes have been proposed to play both protective and deleterious roles in glaucoma. We now show that, within the postlaminar ONH myelination transition zone (MTZ), there are astrocytes that normally express Mac-2 (also known as Lgals3 or galectin-3), a gene typically expressed only in phagocytic cells. Surprisingly, even...
Alternative Titles
Full title
Myelination transition zone astrocytes are constitutively phagocytic and have synuclein dependent reactivity in glaucoma
Authors, Artists and Contributors
Author / Creator
Soto, Ileana
Kim, Keun-Young
Bushong, Eric A.
Oglesby, Ericka
Valiente-Soriano, Francisco J.
Yang, Zhiyong
Davis, Chung-ha O.
Bedont, Joseph L.
Son, Janice L.
Wei, John O.
Buchman, Vladimir L.
Zack, Donald J.
Vidal-Sanz, Manuel
Ellisman, Mark H.
Marsh-Armstrong, Nicholas
Cepko, Constance L.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmed_primary_21199938
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_21199938
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1013965108
