Inhibition of nitric oxide synthase uncoupling by sepiapterin improves left ventricular function in...
Inhibition of nitric oxide synthase uncoupling by sepiapterin improves left ventricular function in streptozotocin-induced diabetic mice
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Publisher
Oxford, UK: Blackwell Publishing Ltd
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Language
English
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Publisher
Oxford, UK: Blackwell Publishing Ltd
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Summary
1. Uncoupling of nitric oxide synthase (NOS) has been implicated in the pathogenesis of left ventricular (LV) dysfunction in diabetes mellitus. In the present study, we investigated the role of NOS uncoupling in oxidative/nitrosative stress and LV dysfunction in the diabetic mouse heart.
2. Diabetes was induced in wild‐type (WT), endo...
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Full title
Inhibition of nitric oxide synthase uncoupling by sepiapterin improves left ventricular function in streptozotocin-induced diabetic mice
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TN_cdi_pubmed_primary_21554376
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_21554376
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ISSN
0305-1870
E-ISSN
1440-1681
DOI
10.1111/j.1440-1681.2011.05535.x
