ATP-sensitive potassium channel (KATP)-dependent regulation of cardiotropic viral infections
ATP-sensitive potassium channel (KATP)-dependent regulation of cardiotropic viral infections
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
The effects of the cellular environment on innate immunity remain poorly characterized. Here, we show that in Drosophila ATP-sensitive potassium channels (KATP) mediate resistance to a cardiotropic RNA virus, Flock House virus (FHV). FHV viral load in the heart rapidly increases in KATP mutant flies, leading to increased viremia and accelerated dea...
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Full title
ATP-sensitive potassium channel (KATP)-dependent regulation of cardiotropic viral infections
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Record Identifier
TN_cdi_pubmed_primary_21719711
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_21719711
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ISSN
0027-8424,1091-6490
E-ISSN
1091-6490
DOI
10.1073/pnas.1108926108
