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Crystal structure of human CD1e reveals a groove suited for lipid-exchange processes

Crystal structure of human CD1e reveals a groove suited for lipid-exchange processes

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_21788486

Crystal structure of human CD1e reveals a groove suited for lipid-exchange processes

About this item

Full title

Crystal structure of human CD1e reveals a groove suited for lipid-exchange processes

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2011-08, Vol.108 (32), p.13230-13235

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

CD1e is the only human CD1 protein existing in soluble form in the late endosomes of dendritic cells, where it facilitates the processing of glycolipid antigens that are ultimately recognized by CD1b-restricted T cells. The precise function of CD1e remains undefined, thus impeding efforts to predict the participation of this protein in the presenta...

Alternative Titles

Full title

Crystal structure of human CD1e reveals a groove suited for lipid-exchange processes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_21788486

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_21788486

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1105627108

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