Inactive-state preassembly of G(q)-coupled receptors and G(q) heterotrimers
Inactive-state preassembly of G(q)-coupled receptors and G(q) heterotrimers
About this item
Full title
Inactive-state preassembly of G(q)-coupled receptors and G(q) heterotrimers
Author / Creator
Publisher
United States
Journal title
Nature chemical biology, 2011-08, Vol.7 (10), p.740
Language
English
Formats
Publication information
Publisher
United States
Subjects
More information
Scope and Contents
Contents
G protein-coupled receptors (GPCRs) transmit signals by forming active-state complexes with heterotrimeric G proteins. It has been suggested that some GPCRs also assemble with G proteins before ligand-induced activation and that inactive-state preassembly facilitates rapid and specific G protein activation. However, no mechanism of preassembly has...
Alternative Titles
Full title
Inactive-state preassembly of G(q)-coupled receptors and G(q) heterotrimers
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmed_primary_21873996
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_21873996
Other Identifiers
E-ISSN
1552-4469
DOI
10.1038/nchembio.642
