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mystery of missing heritability: Genetic interactions create phantom heritability

mystery of missing heritability: Genetic interactions create phantom heritability

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_22223662

mystery of missing heritability: Genetic interactions create phantom heritability

About this item

Full title

mystery of missing heritability: Genetic interactions create phantom heritability

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2012-01, Vol.109 (4), p.1193-1198

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Human genetics has been haunted by the mystery of "missing heritability" of common traits. Although studies have discovered >1,200 variants associated with common diseases and traits, these variants typically appear to explain only a minority of the heritability. The proportion of heritability explained by a set of variants is the ratio of (i) the...

Alternative Titles

Full title

mystery of missing heritability: Genetic interactions create phantom heritability

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_22223662

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_22223662

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1119675109

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