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Sulfonylurea receptor as a target for molecular imaging of pancreas beta cells with (99m)Tc-DTPA-gli...

Sulfonylurea receptor as a target for molecular imaging of pancreas beta cells with (99m)Tc-DTPA-gli...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_22237676

Sulfonylurea receptor as a target for molecular imaging of pancreas beta cells with (99m)Tc-DTPA-glipizide

About this item

Full title

Sulfonylurea receptor as a target for molecular imaging of pancreas beta cells with (99m)Tc-DTPA-glipizide

Publisher

Japan

Journal title

Annals of nuclear medicine, 2012-04, Vol.26 (3), p.253

Language

English

Formats

Publication information

Publisher

Japan

More information

Scope and Contents

Contents

This study was aimed to assess pancreas beta cell activity using (99m)Tc-diethyleneaminepentaacetic acid-glipizide (DTPA-GLP), a sulfonylurea receptor agent. The effect of DTPA-GLP on the blood glucose level in rats was also evaluated.
DTPA dianhydride was conjugated with GLP in the presence of sodium amide, yielding 60%. Biodistribution and pla...

Alternative Titles

Full title

Sulfonylurea receptor as a target for molecular imaging of pancreas beta cells with (99m)Tc-DTPA-glipizide

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_22237676

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_22237676

Other Identifiers

E-ISSN

1864-6433

DOI

10.1007/s12149-011-0569-9

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