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Dichotomous effects of VEGF-A on adipose tissue dysfunction

Dichotomous effects of VEGF-A on adipose tissue dysfunction

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_22451920

Dichotomous effects of VEGF-A on adipose tissue dysfunction

About this item

Full title

Dichotomous effects of VEGF-A on adipose tissue dysfunction

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2012-04, Vol.109 (15), p.5874-5879

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Obese fat pads are frequently undervascularized and hypoxic, leading to increased fibrosis, inflammation, and ultimately insulin resistance. We hypothesized that VEGF-A–induced stimulation of angiogenesis enables sustained and sufficient oxygen and nutrient exchange during fat mass expansion, thereby improving adipose tissue function. Using a doxyc...

Alternative Titles

Full title

Dichotomous effects of VEGF-A on adipose tissue dysfunction

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_22451920

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_22451920

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1200447109

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