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Calcium homeostasis modulator 1 (CALHM1) is the pore-forming subunit of an ion channel that mediates...

Calcium homeostasis modulator 1 (CALHM1) is the pore-forming subunit of an ion channel that mediates...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_22711817

Calcium homeostasis modulator 1 (CALHM1) is the pore-forming subunit of an ion channel that mediates extracellular Ca2+ regulation of neuronal excitability

About this item

Full title

Calcium homeostasis modulator 1 (CALHM1) is the pore-forming subunit of an ion channel that mediates extracellular Ca2+ regulation of neuronal excitability

Publisher

United States: National Acad Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2012-07, Vol.109 (28), p.E1963-E1971

Language

English

Formats

Publication information

Publisher

United States: National Acad Sciences

More information

Scope and Contents

Contents

Extracellular Ca 2+ (Ca 2+ o ) plays important roles in physiology. Changes of Ca 2+ o concentration ([Ca 2+ ] o ) have been observed to modulate neuronal excitability in various physiological and pathophysiological settings, but the mechanisms by which neurons detect [Ca 2+ ] o are not fully understood. Calcium homeostasis modulator 1 (CALHM1) exp...

Alternative Titles

Full title

Calcium homeostasis modulator 1 (CALHM1) is the pore-forming subunit of an ion channel that mediates extracellular Ca2+ regulation of neuronal excitability

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_22711817

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_22711817

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1204023109

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