Acute 5-HT1A autoreceptor knockdown increases antidepressant responses and serotonin release in stre...
Acute 5-HT1A autoreceptor knockdown increases antidepressant responses and serotonin release in stressful conditions
About this item
Full title
Author / Creator
Publisher
Berlin/Heidelberg: Springer-Verlag
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer-Verlag
Subjects
More information
Scope and Contents
Contents
Rationale
Identifying the etiological factors in anxiety and depression is critical to develop more efficacious therapies. The inhibitory serotonin
1A
receptors (5-HT
1A
R) located on 5-HT neurons (autoreceptors) limit antidepressant responses and their expression may be increased in treatment-resistant depressed patients.
Objecti...
Alternative Titles
Full title
Acute 5-HT1A autoreceptor knockdown increases antidepressant responses and serotonin release in stressful conditions
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Record Identifier
TN_cdi_pubmed_primary_22820867
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_22820867
Other Identifiers
ISSN
0033-3158
E-ISSN
1432-2072
DOI
10.1007/s00213-012-2795-9