Infected CD8α⁻ dendritic cells are the predominant source of IL-10 during establishment of persisten...
Infected CD8α⁻ dendritic cells are the predominant source of IL-10 during establishment of persistent viral infection
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Interleukin-10 (IL-10) is an important factor involved in T-cell dysfunction during persistent viral infection. Although several factors can negatively regulate T-cell activity, targeting of the IL-10 pathway alone is sufficient to regenerate T-cell activity and increase viral control. How IL-10 mediates these effects is unclear. Here, we investiga...
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Full title
Infected CD8α⁻ dendritic cells are the predominant source of IL-10 during establishment of persistent viral infection
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TN_cdi_pubmed_primary_22893686
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_22893686
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1211910109
