Genetically controlled upregulation of adenosine A(1) receptor expression enhances the survival of p...
Genetically controlled upregulation of adenosine A(1) receptor expression enhances the survival of primary cortical neurons
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United States
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English
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United States
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Adenosine has a key endogenous neuroprotective role in the brain, predominantly mediated by the adenosine A(1) receptor (A(1)R). This has been mainly explored using pharmacological tools and/or receptor knockout mice strains. It has long been suggested that the neuroprotective effects of A(1)R are increased following receptor upregulation, thus att...
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Genetically controlled upregulation of adenosine A(1) receptor expression enhances the survival of primary cortical neurons
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TN_cdi_pubmed_primary_22899189
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_22899189
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E-ISSN
1559-1182
DOI
10.1007/s12035-012-8321-6