Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner depend...
Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK–SIRT1–PGC1α axis in db/db mice
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Author / Creator
Kim, M. Y. , Lim, J. H. , Youn, H. H. , Hong, Y. A. , Yang, K. S. , Park, H. S. , Chung, S. , Koh, S. H. , Shin, S. J. , Choi, B. S. , Kim, H. W. , Kim, Y. S. , Lee, J. H. , Chang, Y. S. and Park, C. W.
Publisher
Berlin/Heidelberg: Springer-Verlag
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer-Verlag
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More information
Scope and Contents
Contents
Aims/hypothesis
Many of the effects of resveratrol are consistent with the activation of AMP-activated protein kinase (AMPK), silent information regulator T1 (SIRT1) and peroxisome proliferator-activated receptor (PPAR)γ co-activator 1α (PGC-1α), which play key roles in the regulation of lipid and glucose homeostasis, and in the control of oxida...
Alternative Titles
Full title
Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK–SIRT1–PGC1α axis in db/db mice
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmed_primary_23090186
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_23090186
Other Identifiers
ISSN
0012-186X
E-ISSN
1432-0428
DOI
10.1007/s00125-012-2747-2