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Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner depend...

Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner depend...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_23090186

Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK–SIRT1–PGC1α axis in db/db mice

About this item

Full title

Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK–SIRT1–PGC1α axis in db/db mice

Publisher

Berlin/Heidelberg: Springer-Verlag

Journal title

Diabetologia, 2013-01, Vol.56 (1), p.204-217

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer-Verlag

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Aims/hypothesis
Many of the effects of resveratrol are consistent with the activation of AMP-activated protein kinase (AMPK), silent information regulator T1 (SIRT1) and peroxisome proliferator-activated receptor (PPAR)γ co-activator 1α (PGC-1α), which play key roles in the regulation of lipid and glucose homeostasis, and in the control of oxida...

Alternative Titles

Full title

Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK–SIRT1–PGC1α axis in db/db mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmed_primary_23090186

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmed_primary_23090186

Other Identifiers

ISSN

0012-186X

E-ISSN

1432-0428

DOI

10.1007/s00125-012-2747-2

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